Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1(-/y) mouse model of fragile X (FX) suggests that increased constitutive dendritic protein...

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Bibliographic Details
Published in:Mol Psychiatry
Main Authors: Thomazeau, Aurore, Bosch, Miquel, Essayan-Perez, Sofia, Barnes, Stephanie A., De Jesus-Cortes, Hector, Bear, Mark F.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095717/
https://ncbi.nlm.nih.gov/pubmed/32606374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0821-6
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