Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

Metabotropic glutamate receptors (mGluRs) have been implicated in a diverse variety of neuronal functions. Studies reviewed here indicate that exaggerated signalling through mGluR5 can account for multiple cognitive and syndromic features of fragile X syndrome, the most common inherited form of ment...

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Bibliografiske detaljer
Main Authors: Dölen, Gül, Bear, Mark F
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Symposium Section Reports: New Directions in Synaptic and Network Plasticity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375688/
https://ncbi.nlm.nih.gov/pubmed/18202092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.150722
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