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Spike-Driven Glutamate Electrodiffusion Triggers Synaptic Potentiation via a Homer-Dependent mGluR-NMDAR Link

Electric fields of synaptic currents can influence diffusion of charged neurotransmitters, such as glutamate, in the synaptic cleft. However, this phenomenon has hitherto been detected only through sustained depolarization of large principal neurons, and its adaptive significance remains unknown. He...

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Detalhes bibliográficos
Main Authors: Sylantyev, Sergiy, Savtchenko, Leonid P., Ermolyuk, Yaroslav, Michaluk, Piotr, Rusakov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568920/
https://ncbi.nlm.nih.gov/pubmed/23395378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.11.026
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