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The optimal height of the synaptic cleft

Signal integration in the brain is determined by the size and kinetics of rapid synaptic responses. The latter, in turn, depends on the concentration profile of neurotransmitter in the synaptic cleft. According to a traditional view, narrower clefts should correspond to higher intracleft concentrati...

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Detalhes bibliográficos
Main Authors: Savtchenko, Leonid P., Rusakov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783902/
https://ncbi.nlm.nih.gov/pubmed/17261811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606636104
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