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Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging

Neural activity relies on molecular diffusion within nanoscopic spaces outside and inside nerve cells, such as synaptic clefts or dendritic spines. Measuring diffusion on this small scale in situ has not hitherto been possible, yet this knowledge is critical for understanding the dynamics of molecul...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zheng, Kaiyu, Jensen, Thomas P., Savtchenko, Leonid P., Levitt, James A., Suhling, Klaus, Rusakov, Dmitri A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299514/
https://ncbi.nlm.nih.gov/pubmed/28181535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42022
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