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Dual regulation of TRPV1 channels by phosphatidylinositol via functionally distinct binding sites
Regulation of the heat- and capsaicin-activated transient receptor potential vanilloid 1 (TRPV1) channel by phosphoinositides is complex and controversial. In the most recent TRPV1 cryo-EM structure, endogenous phosphatidylinositol (PtdIns) was detected in the vanilloid binding site, and phosphoinos...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8095115/ https://ncbi.nlm.nih.gov/pubmed/33766560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100573 |
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