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A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine

The transient receptor potential channel vanilloid type 1 (TRPV1) is activated by a variety of endogenous and exogenous stimuli and is involved in nociception and body temperature regulation. Although the structure of TRPV1 has been experimentally determined in both the closed and open states, very...

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Vydáno v:J Gen Physiol
Hlavní autoři: Kasimova, Marina A., Yazici, Aysenur Torun, Yudin, Yevgen, Granata, Daniele, Klein, Michael L., Rohacs, Tibor, Carnevale, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219692/
https://ncbi.nlm.nih.gov/pubmed/30333107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812124
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