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A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine

The transient receptor potential channel vanilloid type 1 (TRPV1) is activated by a variety of endogenous and exogenous stimuli and is involved in nociception and body temperature regulation. Although the structure of TRPV1 has been experimentally determined in both the closed and open states, very...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Kasimova, Marina A., Yazici, Aysenur Torun, Yudin, Yevgen, Granata, Daniele, Klein, Michael L., Rohacs, Tibor, Carnevale, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219692/
https://ncbi.nlm.nih.gov/pubmed/30333107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812124
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