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Functional mechanisms of MYRF DNA-binding domain mutations implicated in birth defects
Myrf is a pleiotropic membrane-bound transcription factor that plays critical roles in diverse organisms, including in oligodendrocyte differentiation, embryonic development, molting, and synaptic plasticity. Upon autolytic cleavage, the Myrf N-terminal fragment enters the nucleus as a homo-trimer a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094900/ https://ncbi.nlm.nih.gov/pubmed/33798553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100612 |
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