Carregant...

Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects

Myrf is a membrane-bound transcription factor that plays a key role in various biological processes. The Intramolecular Chaperone Auto-processing (ICA) domain of Myrf forms a homo-trimer, which carries out the auto-cleavage of Myrf. The ICA homo-trimer-mediated auto-cleavage of Myrf is a prerequisit...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: An, Hongjoo, Fan, Chuandong, Sharif, Mohamed, Kim, Dongkyeong, Poitelon, Yannick, Park, Yungki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972908/
https://ncbi.nlm.nih.gov/pubmed/31964908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57593-8
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!