Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice

PURPOSE: Patients with nanophthalmos who undergo intraocular surgery often present with abnormal ciliary zonules. In a previous study, we reported mutation in MYRF that is implicated in the pathogenesis of nanophthalmos. The aim of this study was to model the mutation in mice to explore the role of...

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Bibliografische gegevens
Gepubliceerd in:Invest Ophthalmol Vis Sci
Hoofdauteurs: Yu, Xiaowei, Sun, Nannan, Yang, Xue, Zhao, Zhenni, Su, Xiaoqian, Zhang, Jiamin, He, Yuqing, Lin, Yixiu, Ge, Jian, Fan, Zhigang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Association for Research in Vision and Ophthalmology 2021
Onderwerpen:
Glaucoma
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937999/
https://ncbi.nlm.nih.gov/pubmed/33646289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.3.1
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