Characterization of R132H Mutation‐specific IDH1 Antibody Binding in Brain Tumors

Heterozygous point mutations of isocitrate dehydrogenase (IDH)1 codon 132 are frequent in grade II and III gliomas. Recently, we reported an antibody specific for the IDH1R132H mutation. Here we investigate the capability of this antibody to differentiate wild type and mutated IDH1 protein in centra...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Capper, David, Weißert, Susanne, Balss, Jörg, Habel, Antje, Meyer, Jochen, Jäger, Diana, Ackermann, Ulrike, Tessmer, Claudia, Korshunov, Andrey, Zentgraf, Hanswalter, Hartmann, Christian, Von Deimling, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094636/
https://ncbi.nlm.nih.gov/pubmed/19903171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00352.x
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