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The Nature and Timing of Specific Copy Number Changes in the Course of Molecular Progression in Diffuse Gliomas: Further Elucidation of Their Genetic “Life Story”

Up till now, typing and grading of diffuse gliomas is based on histopathological features. However, more objective tools are needed to improve reliable assessment of their biological behavior. We evaluated 331 diffuse gliomas for copy number changes involving 1p, 19q, CDKN2A, PTEN and EGFR(vIII) by...

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Publicado en:Brain Pathol
Main Authors: Jeuken, Judith W.M., Sijben, Angelique, Bleeker, Fonnet E., Boots‐Sprenger, Sandra H.E., Rijntjes, Jos, Gijtenbeek, Johanna M.M., Mueller, Wolf, Wesseling, Pieter
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094293/
https://ncbi.nlm.nih.gov/pubmed/21029244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00447.x
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