Multiplex Ligation-Dependent Probe Amplification : A Diagnostic Tool for Simultaneous Identification of Different Genetic Markers in Glial Tumors

Genetic aberrations in tumors are predictive for chemosensitivity and survival. A test is needed that allows simultaneous detection of multiple changes and that is widely applicable in a routine diagnostic setting. Multiplex ligation-dependent probe amplification (MLPA) allows detection of DNA copy...

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Главные авторы: Jeuken, Judith, Cornelissen, Sandra, Boots-Sprenger, Sandra, Gijsen, Sabine, Wesseling, Pieter
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2006
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867615/
https://ncbi.nlm.nih.gov/pubmed/16931583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2006.060012
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