Robust Detection of EGFR Copy Number Changes and EGFR Variant III: Technical Aspects and Relevance for Glioma Diagnostics

Epidermal growth factor receptor (EGFR) is commonly affected in cancer, generally in the form of an increase in DNA copy number and/or as mutation variants [e.g., EGFR variant III (EGFRvIII), an in‐frame deletion of exons 2–7]. While detection of EGFR aberrations can be expected to be relevant for g...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Jeuken, Judith, Sijben, Angelique, Alenda, Cristina, Rijntjes, Jos, Dekkers, Marieke, Boots‐Sprenger, Sandra, McLendon, Roger, Wesseling, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332625/
https://ncbi.nlm.nih.gov/pubmed/19744038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00320.x
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