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Atypical Prion Protein Conformation in Familial Prion Disease with PRNP P105T Mutation
Protease‐resistant prion protein (PrP(Sc)) is diagnostic of prion disease, yet its detection is frequently difficult. Here, we describe a patient with a PRNP P105T mutation and typical familial prion disease. Brain PrP(Sc) was undetectable by conventional Western blotting and barely detectable after...
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| 出版年: | Brain Pathol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094255/ https://ncbi.nlm.nih.gov/pubmed/20875062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00439.x |
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