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The Molecular Biology of FMRP: New Insights into Fragile X Syndrome
The Fragile X Mental Retardation 1 protein FMRP is the product of FMR1, a gene whose epigenetic inactivation by a triplet nucleotide repeat expansion causes Fragile X Syndrome (FXS), a neurodevelopmental disorder. FMRP is a widely expressed RNA binding protein whose activity is essential for proper...
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| Publicado no: | Nat Rev Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094212/ https://ncbi.nlm.nih.gov/pubmed/33608673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41583-021-00432-0 |
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