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The Translation of Translational Control by FMRP: Therapeutic Targets for Fragile X Syndrome

De novo protein synthesis is necessary for long-lasting modifications in synaptic strength and dendritic spine dynamics that underlie cognition(1). Fragile X syndrome, characterized by intellectual disability and autistic behaviors, holds promise for revealing the molecular basis for these long-term...

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Bibliografiske detaljer
Main Authors: Darnell, Jennifer C., Klann, Eric
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999698/
https://ncbi.nlm.nih.gov/pubmed/23584741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3379
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