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New Perspectives on the Biology of Fragile X Syndrome

Fragile X syndrome (FXS) is a trinucleotide repeat disorder caused by a CGG repeat expansion in FMR1, and loss of its protein product FMRP. Recent studies have provided increased support for the role of FMRP in translational repression via ribosomal stalling and the microRNA pathway. In neurons, par...

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Autors principals: Wang, Tao, Bray, Steven M., Warren, Stephen T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653273/
https://ncbi.nlm.nih.gov/pubmed/22382129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2012.02.002
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