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Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors
The early events that drive myeloid oncogenesis are not well understood. Most studies focus on the cell-intrinsic genetic changes and how they impact cell fate decisions. We consider how chronic exposure to the proinflammatory cytokine, interleukin-1β (IL-1β), impacts Cebpa-knockout hematopoietic st...
Gardado en:
| Publicado en: | J Exp Med |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094119/ https://ncbi.nlm.nih.gov/pubmed/33914855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200560 |
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