Contrasting Roles for C/EBPα and Notch in Irradiation-Induced Multipotent Hematopoietic Progenitor Cell Defects

Ionizing radiation (IR) is associated with reduced hematopoietic function and increased risk of hematopoietic malignancies, although the mechanisms behind these relationships remain poorly understood. Both effects of IR have been commonly attributed to the direct induction of DNA mutations, but evid...

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Bibliographic Details
Published in:Stem Cells
Main Authors: Fleenor, Courtney Jo, Rozhok, Andrii Ivan, Zaberezhnyy, Vadym, Mathew, Divij, Kim, Jihye, Tan, Aik-Choon, Bernstein, Irwin David, DeGregori, James
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376650/
https://ncbi.nlm.nih.gov/pubmed/25546133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1936
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