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Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis
Aging is associated with the functional decline of cells, tissues, and organs. At the same time, age is the single most important prognostic factor in the development of most human cancers, including chronic myelogenous and acute lymphoblastic leukemias initiated by Bcr-Abl oncogenic translocations....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003039/ https://ncbi.nlm.nih.gov/pubmed/21098275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005486107 |
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