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VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release
Mitochondrial stress (mitostress) triggered by viral infection or mitochondrial dysfunction causes the release of mitochondrial DNA (mtDNA) into the cytosol and activates the cGAS-mediated innate immune response. The regulation of mtDNA release upon mitostress remains uncharacterized. Here, we ident...
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| Udgivet i: | Cell Mol Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8093274/ https://ncbi.nlm.nih.gov/pubmed/33785841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-021-00673-0 |
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