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The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging

The role of mtDNA mutations in aging has been intensely debated because of their low abundance and correlative connection with aging. The creation of mtDNA mutator mice provided the first evidence that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals, and t...

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Detalhes bibliográficos
Main Authors: Edgar, Daniel, Trifunovic, Aleksandra
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815752/
https://ncbi.nlm.nih.gov/pubmed/20157586
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