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The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging

The role of mtDNA mutations in aging has been intensely debated because of their low abundance and correlative connection with aging. The creation of mtDNA mutator mice provided the first evidence that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals, and t...

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Detaylı Bibliyografya
Asıl Yazarlar: Edgar, Daniel, Trifunovic, Aleksandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815752/
https://ncbi.nlm.nih.gov/pubmed/20157586
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