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Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition
Cancers of unknown primary (CUPs), featuring metastatic dissemination in the absence of a primary tumor, are a biological enigma and a fatal disease. We propose that CUPs are a distinct, yet unrecognized, pathological entity originating from stem-like cells endowed with peculiar and shared propertie...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8093243/ https://ncbi.nlm.nih.gov/pubmed/33941777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22643-w |
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