Genotyping tumour DNA in cerebrospinal fluid and plasma of a HER2-positive breast cancer patient with brain metastases

BACKGROUND: Central nervous system (CNS) involvement contributes to significant morbidity and mortality in patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (mBC) and represents a major challenge for clinicians. Liquid biopsy of cerebrospinal fluid (CSF)...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Siravegna, Giulia, Geuna, Elena, Mussolin, Benedetta, Crisafulli, Giovanni, Bartolini, Alice, Galizia, Danilo, Casorzo, Laura, Sarotto, Ivana, Scaltriti, Maurizio, Sapino, Anna, Bardelli, Alberto, Montemurro, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640139/
https://ncbi.nlm.nih.gov/pubmed/29067216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2017-000253
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