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Amyloid Plaques Dissociate Pentameric to Monomeric C‐Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

Beta‐amyloid (Aβ) plaques and local inflammation are central to the pathogenesis of Alzheimer's disease. Although an association between circulating pentameric C‐reactive protein (pCRP) and Alzheimer's disease has been reported no pathomechanistic link has been established. We hypothesized...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Pathol
Hauptverfasser: Strang, Frederik, Scheichl, Amelie, Chen, Yung‐Chih, Wang, Xiaowei, Htun, Nay‐Min, Bassler, Nicole, Eisenhardt, Steffen U., Habersberger, Jonathon, Peter, Karlheinz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092962/
https://ncbi.nlm.nih.gov/pubmed/21951392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00539.x
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