Amyloid Plaques Dissociate Pentameric to Monomeric C‐Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

Beta‐amyloid (Aβ) plaques and local inflammation are central to the pathogenesis of Alzheimer's disease. Although an association between circulating pentameric C‐reactive protein (pCRP) and Alzheimer's disease has been reported no pathomechanistic link has been established. We hypothesized...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Strang, Frederik, Scheichl, Amelie, Chen, Yung‐Chih, Wang, Xiaowei, Htun, Nay‐Min, Bassler, Nicole, Eisenhardt, Steffen U., Habersberger, Jonathon, Peter, Karlheinz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2011
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092962/
https://ncbi.nlm.nih.gov/pubmed/21951392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00539.x
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