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C-reactive protein (CRP) aptamer binds to monomeric but not pentameric form of CRP

Native C-reactive protein (CRP) is composed of five identical subunits arranged in a pentameric structure (pCRP). Binding of pCRP to damaged cell membranes produces a second isoform, modified CRP, which has similar antigenicity to isolated monomeric subunits of CRP (mCRP). Emerging evidence indicate...

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Main Authors: Wang, Min S., Black, Joshua C., Knowles, Michelle K., Reed, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538349/
https://ncbi.nlm.nih.gov/pubmed/21725632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5174-1
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