C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor

While leptin deficiency or dysfunction leads to morbid obesity, obese subjects are characterized paradoxically by hyperleptinemia indicating lack of response to leptin. C-reactive protein (CRP) has been suggested to be a key plasma protein that could bind to leptin. To examine whether CRP interferes...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sudhakar, Manu, Silambanan, Santhi, Chandran, Abhinand S., Prabhakaran, Athira A., Ramakrishnan, Ramya
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992430/
https://ncbi.nlm.nih.gov/pubmed/29910808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01167
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