Amyloid Plaques Dissociate Pentameric to Monomeric C‐Reactive Protein: A Novel Pathomechanism Driving Cortical Inflammation in Alzheimer's Disease?

Beta‐amyloid (Aβ) plaques and local inflammation are central to the pathogenesis of Alzheimer's disease. Although an association between circulating pentameric C‐reactive protein (pCRP) and Alzheimer's disease has been reported no pathomechanistic link has been established. We hypothesized...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Strang, Frederik, Scheichl, Amelie, Chen, Yung‐Chih, Wang, Xiaowei, Htun, Nay‐Min, Bassler, Nicole, Eisenhardt, Steffen U., Habersberger, Jonathon, Peter, Karlheinz
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092962/
https://ncbi.nlm.nih.gov/pubmed/21951392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00539.x
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