Nybomycin Inhibits both Fluoroquinolone-Sensitive and Fluoroquinolone-Resistant Escherichia coli DNA Gyrase

Bacterial type II topoisomerases, DNA gyrase and topoisomerase IV, are targets of many antibiotics, including fluoroquinolones (FQs). Unfortunately, a number of bacterial species easily acquire resistance to FQs by mutations in either DNA gyrase or topoisomerase IV genes. The emergence of resistant...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Shiriaev, Dmitrii I., Sofronova, Alina A., Berdnikovich, Ekaterina A., Lukianov, Dmitrii A., Komarova, Ekaterina S., Marina, Valeriya I., Zakalyukina, Yuliya V., Biryukov, Mikhail V., Maviza, Tinashe P., Ivanenkov, Yan A., Sergiev, Petr V., Osterman, Ilya A., Dontsova, Olga A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Chemistry; Biosynthesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092900/
https://ncbi.nlm.nih.gov/pubmed/33593838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00777-20
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