Nybomycin Inhibits both Fluoroquinolone-Sensitive and Fluoroquinolone-Resistant Escherichia coli DNA Gyrase

Bacterial type II topoisomerases, DNA gyrase and topoisomerase IV, are targets of many antibiotics, including fluoroquinolones (FQs). Unfortunately, a number of bacterial species easily acquire resistance to FQs by mutations in either DNA gyrase or topoisomerase IV genes. The emergence of resistant...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Shiriaev, Dmitrii I., Sofronova, Alina A., Berdnikovich, Ekaterina A., Lukianov, Dmitrii A., Komarova, Ekaterina S., Marina, Valeriya I., Zakalyukina, Yuliya V., Biryukov, Mikhail V., Maviza, Tinashe P., Ivanenkov, Yan A., Sergiev, Petr V., Osterman, Ilya A., Dontsova, Olga A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092900/
https://ncbi.nlm.nih.gov/pubmed/33593838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00777-20
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