Nybomycin Inhibits both Fluoroquinolone-Sensitive and Fluoroquinolone-Resistant Escherichia coli DNA Gyrase

Bacterial type II topoisomerases, DNA gyrase and topoisomerase IV, are targets of many antibiotics, including fluoroquinolones (FQs). Unfortunately, a number of bacterial species easily acquire resistance to FQs by mutations in either DNA gyrase or topoisomerase IV genes. The emergence of resistant...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Shiriaev, Dmitrii I., Sofronova, Alina A., Berdnikovich, Ekaterina A., Lukianov, Dmitrii A., Komarova, Ekaterina S., Marina, Valeriya I., Zakalyukina, Yuliya V., Biryukov, Mikhail V., Maviza, Tinashe P., Ivanenkov, Yan A., Sergiev, Petr V., Osterman, Ilya A., Dontsova, Olga A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Chemistry; Biosynthesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092900/
https://ncbi.nlm.nih.gov/pubmed/33593838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00777-20
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