Nybomycin Inhibits both Fluoroquinolone-Sensitive and Fluoroquinolone-Resistant Escherichia coli DNA Gyrase

Bacterial type II topoisomerases, DNA gyrase and topoisomerase IV, are targets of many antibiotics, including fluoroquinolones (FQs). Unfortunately, a number of bacterial species easily acquire resistance to FQs by mutations in either DNA gyrase or topoisomerase IV genes. The emergence of resistant...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Shiriaev, Dmitrii I., Sofronova, Alina A., Berdnikovich, Ekaterina A., Lukianov, Dmitrii A., Komarova, Ekaterina S., Marina, Valeriya I., Zakalyukina, Yuliya V., Biryukov, Mikhail V., Maviza, Tinashe P., Ivanenkov, Yan A., Sergiev, Petr V., Osterman, Ilya A., Dontsova, Olga A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Chemistry; Biosynthesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092900/
https://ncbi.nlm.nih.gov/pubmed/33593838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00777-20
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