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Therapeutic Potential of Coumestan Pks13 Inhibitors for Tuberculosis
Polyketide synthase 13 (Pks13) is an important enzyme found in Mycobacterium tuberculosis that condenses two fatty acyl chains to produce α-alkyl β-ketoesters, which in turn serve as the precursors for the synthesis of mycolic acids that are essential building blocks for maintaining the cell wall in...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092898/ https://ncbi.nlm.nih.gov/pubmed/33558290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02190-20 |
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