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Viral packaging ATPases utilize a glutamate switch to couple ATPase activity and DNA translocation
Many viruses utilize ringed packaging ATPases to translocate double-stranded DNA into procapsids during replication. A critical step in the mechanochemical cycle of such ATPases is ATP binding, which causes a subunit within the motor to grip DNA tightly. Here, we probe the underlying molecular mecha...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092589/ https://ncbi.nlm.nih.gov/pubmed/33888587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024928118 |
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