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Structure and mechanism of the ATPase that powers viral genome packaging

Many viruses package their genomes into procapsids using an ATPase machine that is among the most powerful known biological motors. However, how this motor couples ATP hydrolysis to DNA translocation is still unknown. Here, we introduce a model system with unique properties for studying motor struct...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hilbert, Brendan J., Hayes, Janelle A., Stone, Nicholas P., Duffy, Caroline M., Sankaran, Banumathi, Kelch, Brian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517215/
https://ncbi.nlm.nih.gov/pubmed/26150523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506951112
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