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Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase
Subunits in multimeric ring-shaped motors must coordinate their activities to ensure correct and efficient performance of their mechanical tasks. Here, we study WT and arginine finger mutants of the pentameric bacteriophage φ29 DNA packaging motor. Our results reveal the molecular interactions neces...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077733/ https://ncbi.nlm.nih.gov/pubmed/30012596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802736115 |
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