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Atypical Molecular Basis for Drug Resistance to Mitochondrial Function Inhibitors in Plasmodium falciparum

The continued emergence of drug-resistant Plasmodium falciparum parasites hinders global attempts to eradicate malaria, emphasizing the need to identify new antimalarial drugs. Attractive targets for chemotherapeutic intervention are the cytochrome (cyt) bc(1) complex, which is an essential componen...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Painter, Heather J., Morrisey, Joanne M., Mather, Michael W., Orchard, Lindsey M., Luck, Cuyler, Smilkstein, Martin J., Riscoe, Michael K., Vaidya, Akhil B., Llinás, Manuel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092505/
https://ncbi.nlm.nih.gov/pubmed/33361312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02143-20
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