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Variation among Plasmodium falciparum Strains in Their Reliance on Mitochondrial Electron Transport Chain Function

Previous studies demonstrated that Plasmodium falciparum strain D10 became highly resistant to the mitochondrial electron transport chain (mtETC) inhibitor atovaquone when the mtETC was decoupled from the pyrimidine biosynthesis pathway by expressing the fumarate-dependent (ubiquinone-independent) y...

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Detalhes bibliográficos
Main Authors: Ke, Hangjun, Morrisey, Joanne M., Ganesan, Suresh M., Painter, Heather J., Mather, Michael W., Vaidya, Akhil B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165440/
https://ncbi.nlm.nih.gov/pubmed/21685321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05049-11
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