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Mitochondrial Electron Transport Inhibition and Viability of Intraerythrocytic Plasmodium falciparum

Although mitochondrial electron transport is a validated target of the antimalarial drug atovaquone, the molecular details underlying parasite demise are unclear. We have shown that a critical function of mitochondrial electron transport in blood-stage Plasmodium falciparum is to support pyrimidine...

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Détails bibliographiques
Auteurs principaux: Painter, Heather J., Morrisey, Joanne M., Vaidya, Akhil B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981233/
https://ncbi.nlm.nih.gov/pubmed/20855748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00937-10
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