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Mitochondrial RNA polymerase is an essential enzyme in erythrocytic stages of Plasmodium falciparum

We have shown that transgenic Plasmodium falciparum parasites expressing the yeast DHODH (dihydroorotate dehydrogenase) are independent of the mtETC (mitochondrial electron transport chain), suggesting that they might not need the mitochondrial genome (mtDNA), since it only encodes three protein sub...

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Detalhes bibliográficos
Main Authors: Ke, Hangjun, Morrisey, Joanne, Ganesan, Suresh M., Mather, Michael W., Vaidya, Akhil B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433233/
https://ncbi.nlm.nih.gov/pubmed/22640832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2012.05.001
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