Atypical Molecular Basis for Drug Resistance to Mitochondrial Function Inhibitors in Plasmodium falciparum

The continued emergence of drug-resistant Plasmodium falciparum parasites hinders global attempts to eradicate malaria, emphasizing the need to identify new antimalarial drugs. Attractive targets for chemotherapeutic intervention are the cytochrome (cyt) bc(1) complex, which is an essential componen...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Painter, Heather J., Morrisey, Joanne M., Mather, Michael W., Orchard, Lindsey M., Luck, Cuyler, Smilkstein, Martin J., Riscoe, Michael K., Vaidya, Akhil B., Llinás, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092505/
https://ncbi.nlm.nih.gov/pubmed/33361312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02143-20
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