A peptide of the N-terminus of GRK5 attenuates pressure-overload hypertrophy and heart failure

Aberrant changes in gene expression underlie the pathogenesis and progression of pressure-overload heart failure, leading to maladaptive cardiac hypertrophy, ventricular remodeling, and contractile dysfunction. Signaling through the G protein Gq triggers maladaptation and heart failure, in part thro...

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Publicado en:Sci Signal
Main Authors: Coleman, Ryan C., Eguchi, Akito, Lieu, Melissa, Roy, Rajika, Barr, Eric W., Ibetti, Jessica, Lucchese, Anna-Maria, Peluzzo, Amanda M., Gresham, Kenneth, Chuprun, J. Kurt, Koch, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092419/
https://ncbi.nlm.nih.gov/pubmed/33785612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abb5968
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