In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection

New vaccines are urgently needed against Mycobacterium tuberculosis (Mtb), which kills more than 1.4 million people each year. CD4 T cell differentiation is a key determinant of protective immunity against Mtb, but it is not fully understood how host-pathogen interactions shape individual antigen-sp...

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Publicado no:mBio
Main Authors: Clemmensen, Helena Strand, Dube, Jean-Yves, McIntosh, Fiona, Rosenkrands, Ida, Jungersen, Gregers, Aagaard, Claus, Andersen, Peter, Behr, Marcel A., Mortensen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092222/
https://ncbi.nlm.nih.gov/pubmed/33879592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00226-21
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