Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

We interrogated at nucleotide resolution the spatiotemporal order of chromatin changes that occur immediately following a site-specific double-strand break (DSB) upstream of the PHO5 locus and its subsequent repair by nonhomologous end joining (NHEJ). We observed the immediate eviction of a nucleoso...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Tripuraneni, Vinay, Memisoglu, Gonen, MacAlpine, Heather K., Tran, Trung Q., Zhu, Wei, Hartemink, Alexander J., Haber, James E., MacAlpine, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092003/
https://ncbi.nlm.nih.gov/pubmed/33811083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.271155.120
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