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Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes
BACKGROUND: Cancer genomes are shaped by mutational processes with complex spatial variation at multiple scales. Entire classes of regulatory elements are affected by local variations in mutation frequency. However, the underlying mechanisms with functional and genetic determinants remain poorly und...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091793/ https://ncbi.nlm.nih.gov/pubmed/33941236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02318-x |
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