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Functional and genetic determinants of mutation rate variability in regulatory elements of cancer genomes
BACKGROUND: Cancer genomes are shaped by mutational processes with complex spatial variation at multiple scales. Entire classes of regulatory elements are affected by local variations in mutation frequency. However, the underlying mechanisms with functional and genetic determinants remain poorly und...
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| Publicat a: | Genome Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091793/ https://ncbi.nlm.nih.gov/pubmed/33941236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02318-x |
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