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Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast

BACKGROUND: Kinases and phosphatases (KP) form complex self-regulating networks essential for cellular signal processing. In spite of having a wealth of data about interactions among KPs and their substrates, we have very limited models of the structures of the directed networks they form and conseq...

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Publicat a:BMC Syst Biol
Autors principals: Abd-Rabbo, Diala, Michnick, Stephen W.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353956/
https://ncbi.nlm.nih.gov/pubmed/28298210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0418-0
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