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Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization

The Staphylococcus aureus Tet38 membrane protein has distinct functions, including drug efflux and host cell attachment and internalization mediated by interaction with host cell CD36. Using structural modeling and site-directed mutagenesis, we identified key amino acids involved in different functi...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Truong-Bolduc, Q. C., Wang, Y., Hooper, D. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091097/
https://ncbi.nlm.nih.gov/pubmed/33619028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00811-20
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