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Tet38 Efflux Pump Contributes to Fosfomycin Resistance in Staphylococcus aureus
Fosfomycin inhibits MurA following uptake by the GlpT transporter of glycerol-3-phosphate in Escherichia coli. In Staphylococcus aureus, plasmid overexpression of the Tet38 efflux pump and a glpT mutant resulted in increased MICs and decreased accumulation of fosfomycin, with MICs affected by glycer...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6105802/ https://ncbi.nlm.nih.gov/pubmed/29891612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00927-18 |
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